Monday, November 23, 2015

Zollinger-Ellison syndrome and Nexium #spon

Zollinger-Ellison syndrome represents group of symptoms that appear due to hypergastrinemia (increased amount of hormone gastrin in blood) which leads to increase of bile acid and ulceration of stomach, intestines and other organs within a body. This is a very rare condition but it can lead to several severe complications including cancer.

Increased secretion of gastrin is usually caused by tumor that is secreting it. These tumors can appear on pancreas and intestines. Sometimes, they affect other parts of the body such as lymph, liver, kidneys, thyroid gland, pituitary gland, ovaries etc. Zollinger-Ellison syndrome can appear as a part of hereditary disease known as multiple endocrine neoplasia type I. In this case, patient will be faced with much more trouble and full recovery will be very hard to accomplish. However, if you buy Nexium online, you will be able to decrease amount of acid which is being produced within the body.

Between 2 to 3 million people in the world have this syndrome. It is equally common for all races and it affects men more than women. Gastrinoma usually appears around age of 45. But, disease usually affects people between 30 and 50 years of age. Prognosis for this condition is usually good and less than 5 % of patients develop complications such as organ perforation, scaring etc.

Symptoms of this illness are non-specific and they usually appear for numerous other conditions as well. This makes it a bit harder for a doctor to diagnose disease at the beginning. List of problems includes pain in upper part of the stomach that resembles ulcer (appearing in two thirds of diseased), frequent diarrhea, bloating, heartburn, loss of appetite which is followed by loss of weight, nausea and vomit, vomiting blood or appearance of black stool.

Making diagnosis based solely on anamnesis is not possible. Doctor will have to perform thorough exam that will show sensitivity of stomach, increase of liver (in case of metastasis), damage to teeth due to long term reflux and discoloration of skin. Gastrin test, as well as test that checks secretion of bile, are being done as a part of routine. Stomach ultrasound (both standard and laparoscopic), CAT scan and pancreas ehtomography show presence of tumor. In medical centers, you can also perform gastroscopy with duodenoscopy (observing interior of stomach area) as well as taking samples for histopathology and microbiologic analysis.

Specialists from You! Drugstore recommend Nexium as one of the best solutions for this particular issue. Besides this condition, drug can also assist with gastroespohageal reflux disease and erosive esophagitis. Have in mind that this drug cannot help patient relieve his immediate heartburn because it cannot work as quickly. Nexium is used with glass full of water, for a period from 4 to 8 weeks. Sometimes, doctor may prescribe it for a longer time. People who suffer from osteoporosis, low level of magnesium in organism, low bone mineral density or liver issue, should consult with a doctor before using this medicine. Side effects of using Nexium are very rare.

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